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HBV 1-2-3!

“HBV Free LV” Campaign Increasing Hepatitis B (HBV) awareness in the Asian and Pacific Islander Communities in Las Vegas.

WHO? WHAT? WHY? HOW?

One in ten Asians and Pacific Islanders are infected with HBV. Majority of these infections are acquired from the mother during childbirth. There is a one in four chance that those infected will die prematurely from cirrhosis or liver cancer. HBV is not curable, however it is suppressible and controllable. The initial step in achieving this is determining who is chronically infected with HBV. Recent CDC guidelines recommend screening of ALL individuals who are Asians or Pacific Islanders. This handbook aims to provide an overview on current screening and therapeutic guidelines for HBV.


STEP 1: Screening

What tests should be ordered? HBsAg and anti-HBs

How should test be interpreted?

-HBsAg
-anti-HBs
VACCINATE (no immunity)
-HBsAg
+anti-HBs
IMMUNE (to HBV)
+HBsAg
-anti-HBs
CHRONIC HBV – go to Step 2

STEP 2: Chronic HBV (+HBsAg)

What tests should be ordered?

What should you counsel patients on?

Consider referral to specialist for further management and therapy.


STEP 3: Guide on interpreting results

-HBV DNA INACTIVE or CARRIER
+HBV DNA+anti-HBc IgM ACUTE INFECTION
++HBV DNA+anti-HBc IgM CHRONIC INFECTION
+HBV DNA+HBeAg HIGHLY INFECTIVE
 +HBV DNA-HBeAg PRE-CORE MUTANT, MAY STILL BE INFECTIVE, STILL HAS ADVANCING DISEASE

The level of HBV DNA is important:


Treatment Guidelines

HEPATITIS B IS NOT CURABLE.

HEPATITIS B IS SUPPRESSIBLE AND CONTROLLABLE.

Rationale for treatment:

Therapy recommended for:

The goals of HBV therapy are:

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